Effects of methylene blue and curcumin photosensitizers on the color stability of endodontically treated intraradicular dentin
Autor: | Cristina Kurachi, Luciano Tavares Angelo Cintra, Vanderlei Salvador Bagnato, Paulo Henrique dos Santos, Henrico Badaoui Strazzi-Sahyon, D. P. Jacomassi, Gustavo Sivieri-Araujo |
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Přispěvatelé: | Universidade Estadual Paulista (UNESP), Universidade de São Paulo (USP) |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Curcumin medicine.medical_treatment Biophysics Color Photodynamic therapy Dermatology TERAPIA FOTODINÂMICA Endodontics chemistry.chemical_compound Materials Testing Dentin medicine Humans Pharmacology (medical) Photosensitizer Staining Methylene blue Photosensitizing Agents Chemistry Significant difference Methylene Blue medicine.anatomical_structure Least significant difference Oncology Photochemotherapy Nuclear chemistry |
Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
ISSN: | 1873-1597 |
Popis: | Made available in DSpace on 2022-04-29T08:36:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01 Background: Photodynamic therapy with photosensitizers can reduce the microbial load. However, few studies have evaluated the effects of photosensitizers on the color stability of endodontically treated intraradicular dentin. This in vitro study investigated the effects of methylene blue and curcumin photosensitizers used in photodynamic therapy on the color stability of intraradicular dentin. Methods: Sixty human incisors were divided into three experimental groups according to the photosensitizer solutions used and their concentrations: methylene blue (25 mg/L), curcumin (1000 mg/L), and curcumin (1500 mg/L). The color stability of endodontically treated intraradicular dentin was evaluated using a portable reflectance spectrophotometer before and after the samples been storage in 2 mL of the photosensitizer solutions during 5 min (n = 20). Color stability data were subjected to a normality test, and statistical analysis was performed using the one-way analysis of variance and Tukey least significant difference test (α = 0.05). Results: Samples treated with 25 mg/L methylene blue photosensitizer showed a higher level of color alteration than those stored in 1000 mg/L curcumin (p = .03322). However, there was no significant difference in the color alteration profiles between the samples treated with 25 mg/L methylene blue and 1500 mg/L curcumin (p = .36428). Furthermore, there was no difference in the color alteration profiles between the dentin samples immersed in 1000 mg/L and 1500 mg/L curcumin photosensitizer solutions (p = .45321). Conclusions: Methylene blue and curcumin photosensitizers influenced the color stability of endodontically treated intraradicular dentin, and this color alteration exceeded the clinical acceptability threshold. Samples treated with 25 mg/L methylene blue showed the highest level of color alteration. Department of Preventive and Restorative Dentistry Discipline of Endodontics Araçatuba School of Dentistry São Paulo State University - UNESP Department of Dental Materials and Prosthodontics Araçatuba School of Dentistry São Paulo State University - UNESP Optic Group Physics Institute of São Carlos - IFSC University of São Paulo – USP Department of Preventive and Restorative Dentistry Discipline of Endodontics Araçatuba School of Dentistry São Paulo State University - UNESP Department of Dental Materials and Prosthodontics Araçatuba School of Dentistry São Paulo State University - UNESP |
Databáze: | OpenAIRE |
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