Review of the first comprehensive outpatient parenteral antimicrobial therapy program in a tertiary care hospital in Japan
| Autor: | Takahiro Mikawa, Naoto Hosokawa, Ryota Hase, Shunsuke Uno, Daisuke Suzuki, Hiroyuki Suzuki, Yoshiaki Yokoyama, Kiyoharu Muranaka |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Methicillin-Resistant Staphylococcus aureus 0301 basic medicine Microbiology (medical) medicine.medical_specialty Adolescent Continuous infusion medicine.drug_class 030106 microbiology Antibiotics Cefazolin Bed days lcsh:Infectious and parasitic diseases Tertiary Care Centers Outpatient parenteral antimicrobial therapy Antimicrobial Stewardship 03 medical and health sciences 0302 clinical medicine Japan Ambulatory Care medicine Humans Antimicrobial stewardship lcsh:RC109-216 Prospective Studies 030212 general & internal medicine Aged Aged 80 and over business.industry Bed days saved Penicillin G General Medicine Middle Aged Tertiary care hospital Antimicrobial Anti-Bacterial Agents Cost savings Infectious Diseases Emergency medicine Female business medicine.drug |
| Zdroj: | International Journal of Infectious Diseases, Vol 95, Iss, Pp 210-215 (2020) |
| ISSN: | 1201-9712 |
| DOI: | 10.1016/j.ijid.2020.03.033 |
| Popis: | Objectives The infectious diseases team at Kameda Medical Center, Japan, implemented a new outpatient parenteral antimicrobial therapy (OPAT) program in July 2012 and expanded the program with the support of home care services. This study reviews the OPAT program after 5.5 years of operation. Methods We prospectively collected data about the age, sex, diagnoses, causative organisms, types of OPAT, modes of administration, selected antibiotics, treatment durations, bed days saved, outcomes, readmissions, and estimated cost reductions of all patients who were treated in the OPAT program from July 2012 to December 2017. Results Of the 66 patients treated under the OPAT program, 45 (68.2%) were treated using clinic OPAT, and 21 (31.8%) were treated using homecare OPAT. The most commonly targeted organism was methicillin-susceptible Staphylococcus aureus. Continuous infusion with elastomeric pumps was employed in 55 patients (83.3%). Cefazolin was the most frequently used antibiotic (39.4%), followed by penicillin G (24.2%). The median OPAT duration was 13 days (range, 3–51), and the total bed days saved was 923. The estimated medical cost reduction was approximately 87,000 US dollars. Conclusions Our experience shows that OPAT is a safe and feasible practice not only for efficient bed utilization and medical cost savings but also for better antimicrobial stewardship. |
| Databáze: | OpenAIRE |
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