Mechanism and inhibition of abnormal chromatographic behavior of serotype type a inactivated foot and mouth disease virus in high-performance size-exclusion chromatography

Autor: Yanli Yang, Ming Li, Yi Zhao, Xuan Lin, Zhiguo Su, Fei Xin, Xiaojie Du, Kan Zheng, Rui Han, Yiping Pan, Sun He, Songping Zhang
Rok vydání: 2022
Předmět:
Zdroj: Journal of Chromatography A. 1686:463648
ISSN: 0021-9673
Popis: High-performance size-exclusion chromatography (HPSEC) has been developed for the rapid and quantitative analysis of inactivated foot and mouth disease virus (FMDV) and adopted by regulatory agencies and vaccine manufacturers. However, strong non-specific adsorption of type A/AKT III FMDV was found on some batches of TSK G4000 SW
Databáze: OpenAIRE