Risk factors associated with surgical site infections after thoracic or lumbar surgery: a 6-year single centre prospective cohort study

Autor: Ondrej Bradac, Daniela Fackova, Jan Hradil, Vera Spatenkova, Milada Halacova, Zdenek Jindrisek
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Hot Temperature
Time Factors
Wound complications
Diseases of the musculoskeletal system
Logistic regression
Thoracic Vertebrae
03 medical and health sciences
Postoperative Complications
Spine surgery
0302 clinical medicine
Lumbar
Risk Factors
Internal medicine
medicine
Humans
Surgical Wound Infection
Orthopedic Procedures
Orthopedics and Sports Medicine
Prospective Studies
030212 general & internal medicine
Antibiotic prophylaxis
Prospective cohort study
Orthopedic surgery
Infection Control
Lumbar Vertebrae
business.industry
Incidence
Incidence (epidemiology)
Length of Stay
Logistic Models
RC925-935
Multivariate Analysis
Female
Surgery
Seasons
Preventive infection protocol
business
Body mass index
Surgical site infection
RD701-811
030217 neurology & neurosurgery
Research Article
Cohort study
Zdroj: Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Journal of Orthopaedic Surgery and Research
ISSN: 1749-799X
Popis: Background Surgical site infection (SSI) is a risk in every operation. Infections negatively impact patient morbidity and mortality and increase financial demands. The aim of this study was to analyse SSI and its risk factors in patients after thoracic or lumbar spine surgery. Methods A six-year single-centre prospective observational cohort study monitored the incidence of SSI in 274 patients who received planned thoracic or lumbar spinal surgery for degenerative disease, trauma, or tumour. They were monitored for up to 30 days postoperatively and again after 1 year. All patients received short antibiotic prophylaxis and stayed in the eight-bed neurointensive care unit (NICU) during the immediate postoperative period. Risk factors for SSI were sought using multivariate logistic regression analysis. Results We recorded 22 incidences of SSI (8.03%; superficial 5.84%, deep 1.82%, and organ 0.36%). Comparing patients with and without SSI, there were no differences in age (p=0.374), gender (p=0.545), body mass index (p=0.878), spine diagnosis (p=0.745), number of vertebrae (p=0.786), spine localization (p=0.808), implant use (p=0.428), American Society of Anesthesiologists (ASA) Score (p=0.752), urine catheterization (p=0.423), drainage (p=0.498), corticosteroid use (p=0.409), transfusion (p=0.262), ulcer prophylaxis (p=0.409) and diabetes mellitus (p=0.811). The SSI group had longer NICU stays (p=0.043) and more non-infectious hospital wound complications (ppp=0.044). Conclusions Contrary to the prevailing literature, our study did not identify corticosteroids, diabetes mellitus, or transfusions as risk factors for the development of SSI. Only wound complications and warm seasons were significantly associated with SSI development according to our multivariate regression analysis.
Databáze: OpenAIRE
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