Pauciarticular severe destructive arthropathy in a child secondary to synovial osteochondromatosis
| Autor: | Tamer A. Gheita, Yasser Ragab, F. Zeinhom, Yasser Emad |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
musculoskeletal diseases
Male Pathology medicine.medical_specialty Adolescent Knee Joint Arthroscopy Rheumatology Synovial osteochondromatosis Arthropathy medicine Humans medicine.diagnostic_test business.industry Hyaline cartilage Ossification Cartilage Arthritis General Medicine musculoskeletal system medicine.disease Tendon sheath medicine.anatomical_structure Chondromatosis medicine.symptom business Chondromatosis Synovial Ankle Joint |
| Zdroj: | Clinical rheumatology. 26(4) |
| ISSN: | 0770-3198 |
| Popis: | Synovial osteochondromatosis (SOC) is a benign neoplasm characterized by synovial proliferation and chondrometaplasia and may affect the synovial lining of a joint, bursa, or tendon sheath. The disease is usually monoarticular. Joints mostly affected are knee, hip, shoulder, elbow and ankle. The affected synovium undergoes metaplastic transformation into cartilage forming chondroblasts, which mature into chondrocytes to form nodules of hyaline cartilage [1]. Immunohistological studies showed that these cartilaginous loose bodies are the result of metaplasia of the synovium. The histologic appearance of this process shows well-defined cartilage nests embedded in a layer of synovium. There may be significant pleomorphism. There may be evidence of advancing stageswithmaturation of the cartilage with mineralization and ossification [2]. Usual clinical presentation is that of intermittent joint pains, swelling, stiffness and restriction of movements and instability. Occasionally, locking or internal derangement due to impingement by loose body may be the presenting symptom, this being more common in the knee where it may mimic a meniscal tear [1]. |
| Databáze: | OpenAIRE |
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