NK/T‑cell non‑Hodgkin lymphoma: Case report and review of the literature
| Autor: | Anca Telehuz, Elena Niculet, Violeta Sapira, Doina Carina Voinescu, Angel Liviu Trifan, Eva Maria Elkan, Mihai Polinschi, Gabriela Stoleriu, Ana Fătu, Mihaiela Lungu, Valerica Zarnescu Creanga |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty T cell 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) Ptosis medicine intra-orbital lymphoma Extranodal Involvement Mycosis fungoides NK/T-cell non-Hodgkin lymphoma mycosis fungoides business.industry Cancer Articles General Medicine NKTCL medicine.disease NKTCL cutaneous expression Dermatology Lymphoma 030104 developmental biology medicine.anatomical_structure T-Cell Non-Hodgkin Lymphoma 030220 oncology & carcinogenesis Etiology NKTCL neurological expression medicine.symptom business |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2020.9523 |
| Popis: | Natural killer (NK)/T-cell lymphomas represent a rare type of lymphoid malignancy with mostly extranodal involvement, having NK cell or (rare) T cell lineage, classified by the World Health Organization into several subtypes which can involve the head and neck region, with the most frequent one being the nasal type. This article presents the case of a 31-year-old patient who presented at the Emergency Unit of Saint Andrew Emergency Clinical Hospital of Galati suffering from mycosis fungoides-like cutaneous lesions, associated with partial left eyelid ptosis of unknown etiology, as well as a poor health status with fever and respiratory failure. The final diagnosis was NK/T-cell non-Hodgkin lymphoma, possibly nasal type with medium sized T cells. The complexity of the rare diagnosis, associated with the unusual rapid patient evolution towards exitus 3 months after diagnosis, the intra-orbital metastatic involvement and the absence of a standardized treatment are case peculiarities, some of which are consistent with current literature data. |
| Databáze: | OpenAIRE |
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