Integrated 18F-fluorodeoxyglucose positron emission tomography and computerized tomography in endodermal sinus tumor

Autor: J. B. Lessing, C. Klieger, Einat Even-Sapir, R. Dvir, Dan Grisaru, Y. Burstein
Rok vydání: 2006
Předmět:
Zdroj: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 16(4)
ISSN: 1048-891X
Popis: Application of an in-line positron emission tomography and computerized tomography (PET-CT) in endodermal sinus tumor (EST) is described in this study. CASE 1: A young female with massive ascites postovarian mass resection had elevated alpha-fetoprotein (AFP) serum levels. Following a positive PET-CT study with increased (18)F-fluorodeoxyglucose (FDG) uptake, a CT-guided core biopsy of a peritoneal mass was performed. EST was diagnosed histologically. The patient was disease free after chemotherapy. Follow-up PET-CT was negative in keeping with no viable tumor tissue. CASE 2: A large pelvic mass diagnosed histologically as primarily EST was removed in a teenage patient with elevated AFP levels. PET-CT showed diffuse abdominal spread of FDG uptake, suggesting extensive peritoneal seeding. The patient was disease free after chemotherapy. Follow-up PET-CT was negative. EST is an FDG-avid tumor. PET-CT delineated the prechemotherapy tumor extent adequately ruled out the presence of residual tumor after a successful treatment.
Databáze: OpenAIRE