Growth Differentiation Factor-15 as a Predictor of Functional Capacity, Frailty, and Ventricular Dysfunction in Patients With Aortic Stenosis and Preserved Left Ventricular Ejection Fraction

Autor:	Lauren, Basmadjian, Nadia, Bouabdallaoui, François, Simard, Eileen, O'Meara, Anique, Ducharme, Jean-Lucien, Rouleau, Normand, Racine, Michel, White, Martin G, Sirois, Anita, Asgar, Reda, Ibrahim, Jean-François, Dorval, Raoul, Bonan, Raymond, Cartier, Jessica, Forcillo, Ismail, El-Hamamsy, Christine, Henri
Rok vydání:	2023
Předmět:	Ventricular Dysfunction Left Growth Differentiation Factor 15 Frailty Ventricular Remodeling Risk Factors Humans Stroke Volume Aortic Valve Stenosis Cardiology and Cardiovascular Medicine Ventricular Function Left
Zdroj:	The American Journal of Cardiology. 186:11-16
ISSN:	0002-9149
Popis:	In aortic stenosis (AS), left ventricular (LV) remodeling often occurs before symptom onset, and early intervention may be beneficial. Risk stratification remains challenging and identification of biomarkers may be useful. We evaluated the association between growth differentiation factor-15 (GDF-15) and soluble suppression of tumorigenicity 2 (sST2) and known markers of poor prognosis in AS. Baseline plasma GDF-15 and sST2 levels were measured in 70 patients with moderate-severe AS (aortic valve area1.5 cm
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5c5a65aec971e526238b5bdd656586 https://doi.org/10.1016/j.amjcard.2022.09.029 Zobrazit plný text záznamu Full Text from ScienceDirect