Middle Cerebral Artery Peak Systolic Velocity in Monochorionic and Dichorionic Twin Pregnancies
Autor: | Jodi S. Dashe, Diane M. Twickler, Donald D. McIntire, Ronald M. Ramus, Rigoberto Santos-Ramos |
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Rok vydání: | 2007 |
Předmět: |
Adult
Middle Cerebral Artery medicine.medical_specialty genetic structures Anemia Birth weight Twins Blood Pressure Sensitivity and Specificity Ultrasonography Prenatal Pregnancy Internal medicine medicine.artery medicine Humans Radiology Nuclear Medicine and imaging Prospective cohort study Retrospective Studies Fetus Radiological and Ultrasound Technology business.industry Reproducibility of Results Prognosis medicine.disease Twin study Surgery Middle cerebral artery Cardiology Gestation Female business Blood Flow Velocity circulatory and respiratory physiology |
Zdroj: | Journal of Ultrasound in Medicine. 26:195-200 |
ISSN: | 0278-4297 |
DOI: | 10.7863/jum.2007.26.2.195 |
Popis: | Objective The purpose of this study was to compare middle cerebral artery (MCA) peak systolic velocity (PSV) values in monochorionic (MC) and dichorionic (DC) twin pregnancies. Methods This was a prospective cohort study in which MCA Doppler evaluation was performed in unselected twin pregnancies at time of routine sonography between 28 and 32 weeks. Pregnancies with known fetal anomalies, twin-twin transfusion syndrome, and red cell alloimmunization or other conditions associated with anemia were excluded. The intertwin MCA PSV difference, defined as the larger minus smaller PSV value within a pair, was compared in MC and DC pregnancies and was correlated with estimated fetal weight and birth weight discordance. Statistical analyses included Spearman correlation, analysis of variance, a t test, and a chi(2) test. Results Doppler indices were analyzed from 48 twin pregnancies, of which 32 (67%) were DC and 16 (33%) were MC. There was no difference in proportion of values above or below the singleton median for either the larger or smaller DC or MC twins (all P > or = .3). The median intertwin MCA PSV difference was 4.9 cm/s in MC pregnancies and 4.5 cm/s in DC pregnancies (P = .6). There was no significant correlation between the MCA PSV difference and either estimated fetal weight discordance or birth weight discordance in either MC or DC pregnancies (all P > or = .3). Conclusions Middle cerebral artery PSV values in uncomplicated twin pregnancies are comparable with published singleton norms, with a median intertwin MCA PSV difference of approximately 5 cm/s. We found no significant correlation between the intertwin MCA PSV difference and discordance in MC or DC twin gestations. |
Databáze: | OpenAIRE |
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