Neoadjuvant Chemotherapy does not Increase Complications in Oncoplastic Breast-Conserving Surgery
| Autor: | Jun Liu, Donald P. Baumann, Benjamin Smith, Mark V. Schaverien, Mariana Chavez-MacGregor, Abigail S. Caudle, Karri A. Adamson |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Breast Neoplasms 030230 surgery Mastectomy Segmental 03 medical and health sciences Young Adult 0302 clinical medicine Breast cancer Postoperative Complications Risk Factors Antineoplastic Combined Chemotherapy Protocols medicine Breast-conserving surgery Humans Aged Retrospective Studies business.industry Mastopexy Cancer Retrospective cohort study Middle Aged medicine.disease Prognosis Chemotherapy regimen Combined Modality Therapy Neoadjuvant Therapy Surgery Oncology Chemotherapy Adjuvant 030220 oncology & carcinogenesis Female Breast reduction business Mastectomy Follow-Up Studies |
| Zdroj: | Annals of surgical oncology. 26(9) |
| ISSN: | 1534-4681 |
| Popis: | Oncoplastic breast-conserving surgery (OBCS) broadens the indications for breast conservation. Neoadjuvant systemic chemotherapy (NAC) is used increasingly in the treatment of patients with early-stage and locally advanced breast cancer. This study aimed to evaluate the outcomes for patients who received NAC followed by OBCS. A retrospective chart review was performed for all patients who underwent OBCS involving the mastopexy/breast-reduction technique, including synchronous mastopexy/breast reduction for symmetry, at the University of Texas MD Anderson Cancer Center between January 2010 and January 2016. Patients who had received NAC were compared with those who had undergone surgery first. Demographic, treatment, and outcomes data were collected. The study included 429 patients, corresponding to 713 breasts. Of these patients, 122, corresponding to 199 breasts, received NAC. The patients who received NAC were younger (p |
| Databáze: | OpenAIRE |
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