Improved Sexual Function During Recombinant Human Erythropoietin Therapy
| Autor: | H. P. Barth, R. Seelig, Jürgen Bommer, Eberhard Ritz, B. Schwöbel, M. Kugel |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Sexual partner medicine.medical_specialty Sexual Behavior Renal Dialysis Surveys and Questionnaires Internal medicine medicine Humans Gonadal Steroid Hormones Erythropoietin Testosterone Libido Transplantation business.industry Maintenance dose Middle Aged Recombinant Proteins Prolactin Endocrinology Hematocrit Nephrology business Sexual function hormones hormone substitutes and hormone antagonists Hormone medicine.drug |
| Zdroj: | Nephrology Dialysis Transplantation. 5:204-207 |
| ISSN: | 1460-2385 0931-0509 |
| DOI: | 10.1093/ndt/5.3.204 |
| Popis: | In seven male haemodialysis patients, living with a constant sexual partner, sexual life (self-administered questionnaire) and sex hormones were evaluated before and 3 or 10 months after commencement of recombinant human erythropoietin (rHuEpo) therapy respectively. Haematocrit increased from 22.2 +/- 2.1% to 30.6 +/- 1% with a maintenance dose of 140 +/- 55 U/kg per week. Two patients were hypertensive before and after rHuEpo therapy; antihypertensive medication was kept constant during the study. Self-reported sexual function improved in four of seven patients, including libido and erection. This was paralleled by improved indices of wellbeing (physical fitness, mental alertness). In contrast, serum values of sexual hormones (testosterone or oestradiol) and of basal and stimulated (LHRH/TRH), prolactin and LH, and FSH were not significantly changed during rHuEpo therapy. |
| Databáze: | OpenAIRE |
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