Clonal stability and mutation in the self-fertilizing hermaphroditic fish, Rivulus marmoratus
| Autor: | Thomas F. Laughlin, D. S. Taylor, E.-H. Park, B. A. Lubinski, Bruce J. Turner |
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| Rok vydání: | 1995 |
| Předmět: |
Mutation rate
Population Molecular Sequence Data Restriction Mapping Genetics Animals Hermaphroditic Organisms education Molecular Biology Genetics (clinical) education.field_of_study Extinction Polymorphism Genetic biology Base Sequence Fishes Sex Determination Processes biology.organism_classification Rivulus DNA Fingerprinting Transplantation DNA profiling Evolutionary biology Mutation (genetic algorithm) Mutation Fish Female Oligonucleotide Probes Biotechnology |
| Zdroj: | The Journal of heredity. 86(5) |
| ISSN: | 0022-1503 |
| Popis: | Previous investigations of natural populations of the hermaphroditic, self-fertilizing fish species Rivulus marmoratus demonstrated a surprising amount of interclonal differentiation among highly polymorphic "DNA fingerprint" loci. The genetic differentiation observed among clones was thought to be the effect of extreme population mixing because of high rates of migration and population extinction. It was demonstrated that mutation rates at hypervariable loci would have to exceed 10(-4) on average to alone account for the observed interclonal differences. The present study reports that, among laboratory lines of this species, mutation rates at the most unstable set of hypervariable loci are not greater than 3.52 x 10(-4), and are probably lower. Mutation rates at several other sets of loci are even lower. A field transplantation study demonstrated complete clonal stability over several generations. These results suggest that the high interclonal differences observed in natural populations of this species is not caused by a generally higher rate of mutation at these specific loci. |
| Databáze: | OpenAIRE |
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