Single- and dual-energy CT with monochromatic synchrotron x-rays
| Autor: | D.J. Krus, Terry M. Button, Jeffrey A. Coderre, E C Parsons, William Thomlinson, X. Y. Wu, F.A. Dilmanian, Zhong Zhong, F. Giron, Zhengrong Liang, Daniel N. Slatkin, L. D. Chapman, M.J. Petersen, D. Greenberg, C.T. Roque, K. Yamamoto, S Marcovici, J. Kress, B. Ren, M. Shleifer |
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| Rok vydání: | 1997 |
| Předmět: |
Imaging phantom
law.invention Optics law Image noise Animals Humans Computer Simulation Radiology Nuclear Medicine and imaging Image resolution Physics Radiological and Ultrasound Technology Phantoms Imaging business.industry X-Rays Equipment Design Synchrotron Image contrast Acrylates K-edge Rabbits Dual energy ct Monochromatic color Tomography X-Ray Computed business Nuclear medicine Head Neck Synchrotrons Iodine |
| Zdroj: | Physics in Medicine and Biology. 42:371-387 |
| ISSN: | 1361-6560 0031-9155 |
| DOI: | 10.1088/0031-9155/42/2/009 |
| Popis: | We explored the potential for clinical research of computed tomography (CT) with monochromatic x-rays using the preclinical multiple energy computed tomography (MECT) system at the National Synchrotron Light Source. MECT has a fixed, horizontal fan beam with a subject apparatus rotating about a vertical axis; it will be used for imaging the human head and neck. Two CdWO4-photodiode array detectors with different spatial resolutions were used. A 10.5 cm diameter acrylic phantom was imaged with MECT at 43 keV and with a conventional CT (CCT) at 80 kVp: spatial resolution approximately equal to 6.5 line pairs (lp)/cm for both; slice height, 2.6 mm for MECT against 3.0 mm for CCT; surface dose, 3.1 cGy for MECT against 2.0 cGy for CCT. The resultant image noise was 1.5 HU for MECT against 3 HU for CCT. Computer simulations of the same images with more precisely matched spatial resolution, slice height and dose indicated an image-noise ratio of 1.4:1.0 for CCT against MECT. A 13.5 cm diameter acrylic phantom imaged with MECT at approximately 0.1 keV above the iodine K edge and with CCT showed, for a 240 micrograms I ml-1 solution, an image contrast of 26 HU for MECT and 13 and 9 HU for the 80 and 100 kVp CCT, respectively. The corresponding numbers from computer simulation of the same images were 26, 12, and 9 HU, respectively. MECT's potential for use in clinical research is discussed. |
| Databáze: | OpenAIRE |
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