Giant Cell Arteritis (GCA): Pathogenesis, Clinical Aspects and Treatment Approaches
| Autor: | Giannicola Iannella, Antonio Greco, Giampiero Gulotta, Alessandra Manno, Andrea Ciofalo, Marco de Vincentiis, Annalisa Pace, Benedetta Pasquariello, Diletta Angeletti, Giancarlo Altissimi, Giuseppe Magliulo |
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| Rok vydání: | 2019 |
| Předmět: |
030203 arthritis & rheumatology
Autoimmune disease Pathology medicine.medical_specialty business.industry Giant Cell Arteritis autoimmune disease giant cell arteritis ENT audiovestibular abnormalities hearing loss Disease Prognosis medicine.disease Pathogenesis Polymyalgia rheumatica Otorhinolaryngologic Diseases 03 medical and health sciences Giant cell arteritis 0302 clinical medicine Rheumatology Adrenal Cortex Hormones Occlusion medicine Humans Arteritis Vasculitis business 030217 neurology & neurosurgery |
| Zdroj: | Current Rheumatology Reviews. 15:259-268 |
| ISSN: | 1573-3971 |
| Popis: | Giant Cell Arteritis (GCA), or Horton’s Arteritis, is a chronic form of vasculitis of the large and medium vessels, especially involving the extracranial branches of the carotid arteries, in particular, the temporal artery, with the involvement of the axillary, femoral and iliac arteries too. Arterial wall inflammation leads to luminal occlusion and tissue ischemia, which is responsible for the clinical manifestations of the disease. : A substantial number of patients affected by GCA present head and neck symptoms, including ocular, neurological and otorhinolaryngological manifestations. : The aim of this article is to present pathogenesis, clinical aspects and treatment approaches of GCA manifestations. |
| Databáze: | OpenAIRE |
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