Reduced Nogo-P3 in adults with developmental coordination disorder (DCD)

Autor: Yoshimi Kaga, Yosuke Kita, Kota Suzuki, Hideyuki Okuzumi, Masumi Inagaki, Yuka Egashira, Yuka Shirakawa, Shota Mitsuhashi, Yuzuki Kitamura
Přispěvatelé: Medicum, Faculty of Medicine, University of Helsinki, Cognitive Brain Research Unit
Rok vydání: 2020
Předmět:
DYNAMICS
Adult
Male
medicine.medical_specialty
MOTOR INHIBITION
CHILDREN
Audiology
Motor Activity
Movement assessment
050105 experimental psychology
Task (project management)
Developmental coordination disorder
03 medical and health sciences
Executive Function
Young Adult
0302 clinical medicine
Event-related potential
Physiology (medical)
Motor clumsiness
mental disorders
Medicine
Humans
0501 psychology and cognitive sciences
UTAH RATING-SCALE
Motor clumsy
Inhibition
CONFLICT
HOT EXECUTIVE FUNCTION
business.industry
General Neuroscience
05 social sciences
1184 Genetics
developmental biology
physiology
ATTENTION
Cognition
Electroencephalography
Event-Related Potentials
P300
Motor Skills Disorders
Inhibition
Psychological
Neuropsychology and Physiological Psychology
STOP-SIGNAL PARADIGM
Cognitive control
TASK
Female
business
RESPONSE-INHIBITION
030217 neurology & neurosurgery
psychological phenomena and processes
Psychomotor Performance
Event-related potentials
Zdroj: International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 153
ISSN: 1872-7697
Popis: Nogo-N2 is associated with the premotor cognitive process that precedes motor response (e.g., conflict monitoring), whereas Nogo-P3 is related to the inhibition of the actual motor response. We examined the influence of motor clumsiness of developmental coordination disorder (DCD) on components of the event-related potential in a Go/Nogo task. Participants were healthy adults (N = 81) that were classified into control and DCD groups based on the Movement Assessment Battery for Children Second Edition. We manipulated the difficulty in stopping a response by varying the frequency of Nogo stimuli in a response task into rare (20%) and frequent (80%) conditions, and Nogo-N2 and Nogo-P3 were calculated from electroencephalograms (EEGs) during the Go/Nogo tasks. The commission error rate in the rare condition was significantly higher in the DCD group than in the control group, indicating that motor clumsiness decreases task performance. There were no differences in Nogo-N2 between DCD and control groups. However, Nogo-P3 in the rare condition was reduced in the DCD group compared to the control group. These results suggest that the influence of motor clumsiness is limited to the cognitive process after the initiation of the actual motor response.
Databáze: OpenAIRE
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