Concurrent group treatment for hepatitis C: Implementation and outcomes in a methadone maintenance treatment program
Autor: | Robert J. Roose, Melissa R. Stein, Irene Soloway, Alain H. Litwin, Julia H. Arnsten, Karen S. Jefferson |
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Rok vydání: | 2012 |
Předmět: |
Adult
Male Drug medicine.medical_specialty Methadone maintenance Genotype Side effect media_common.quotation_subject Medicine (miscellaneous) Physical examination Hepacivirus Antiviral Agents Article Medication Adherence Polyethylene Glycols Pharmacotherapy Internal medicine Ribavirin Opiate Substitution Treatment medicine Humans Retrospective Studies media_common medicine.diagnostic_test Heroin Dependence business.industry Interferon-alpha Retrospective cohort study Hepatitis C Hepatitis C Chronic Middle Aged Viral Load medicine.disease Recombinant Proteins Surgery Psychiatry and Mental health Clinical Psychology Treatment Outcome Psychotherapy Group Drug Therapy Combination Female Pshychiatric Mental Health business Viral load Methadone |
Zdroj: | Journal of Substance Abuse Treatment. 43:424-432 |
ISSN: | 0740-5472 |
Popis: | Chronic hepatitis C virus (HCV) infection is highly prevalent among current and former drug users. However, the minority of patients enrolled in drug treatment programs have initiated HCV treatment. New models are needed to overcome barriers to care. In this retrospective study, we describe the implementation and outcomes of 42 patients treated in a concurrent group treatment (CGT) program. Patients participated in weekly provider-led group treatment sessions which included review of side effects; discussion of adherence and side effect management; administration of interferon injections; brief physical examination; and ended with brief meditation. Of the first 27 patients who initiated CGT, 42% achieved a sustained viral response. In addition, 87% (13/15) of genotype-1 infected patients treated with direct acting antiviral agent achieved an undetectable viral load at 24 weeks. The CGT model may be effective in overcoming barriers to treatment and improving adherence and outcomes among patients enrolled in drug treatment programs. |
Databáze: | OpenAIRE |
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