Detection of coronary plaque by computed tomography with a novel plaque analysis system, 'Plaque Map', and comparison with intravascular ultrasound and angioscopy
| Autor: | Kazuhisa Kodama, Yasuo Fujisawa, Sei Komatsu, Yasunori Ueda, Yosuke Omori, Isamu Mizote, Atsushi Hirayama, Toshiaki Higashide, Masayoshi Kiyomoto |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome medicine.medical_treatment Myocardial Infarction Angioscopy Coronary Disease Sensitivity and Specificity Intravascular ultrasound medicine Humans cardiovascular diseases Myocardial infarction medicine.diagnostic_test business.industry Unstable angina Coronary Stenosis Percutaneous coronary intervention Calcinosis Reproducibility of Results General Medicine Middle Aged medicine.disease medicine.anatomical_structure Female Tomography Radiology Cardiology and Cardiovascular Medicine business Tomography X-Ray Computed Artery |
| Zdroj: | Circulation journal : official journal of the Japanese Circulation Society. 69(1) |
| ISSN: | 1346-9843 |
| Popis: | Background Previous reports suggest that plaque may be characterized by the computed tomography (CT) number, but there is not a comprehensive method for evaluating the gray-scale CT image of the coronary artery obtained by multi-detector row CT (MDCT). Methods and Results Forty-five patients with acute coronary syndrome (ACS) underwent MDCT either 3-4 weeks after the onset of acute myocardial infarction (n=24) or within 1 week after percutaneous coronary intervention in patients with unstable angina (UA; n=21). The cross-sections obtained at intervals of 5 mm were converted to numerical data and a `plaque map' was drawn using the color-based isometric line method and bird's eye view. `Plaque map' was compared with the findings of intravascular ultrasound (IVUS) and angioscopy. Of 662 slices of 78 vessels, soft, intermediate or calcified plaque was detected in 144, 134, and 84 slices, respectively. Compared with IVUS, the sensitivities were 92%, 87%, and 89%, respectively, and compared with angioscopy, sensitivity was 80% and specificity was 87%. Conclusions MDCT with the `Plaque Map' system can noninvasively characterize plaque in patients with ACS. (Circ J 2005; 69: 72 - 77) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|