Hyperspectral imaging as a possible tool for visualization of changes in hemoglobin oxygenation in patients with deficient hemodynamics – proof of concept
| Autor: | Georg Daeschlein, Markus Kretching, Thomas Wild, S. Lutze, Claudia Sicher, Sebastian von Podewils, Rico Rutkowski |
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| Rok vydání: | 2018 |
| Předmět: |
Diagnostic Imaging
medicine.medical_specialty 0206 medical engineering Biomedical Engineering Hemodynamics Dermatitis 02 engineering and technology 01 natural sciences Microcirculation 010309 optics 0103 physical sciences medicine Humans Distribution (pharmacology) Abscess Skin Oxygen saturation (medicine) business.industry Oxygenation medicine.disease 020601 biomedical engineering Radiology Hemoglobin business Perfusion |
| Zdroj: | Biomedical Engineering / Biomedizinische Technik. 63:609-616 |
| ISSN: | 1862-278X 0013-5585 |
| DOI: | 10.1515/bmt-2017-0084 |
| Popis: | There is a lack of imaging tools for the evaluation of spatial alterations in microcirculation including blood oxygen saturation and hemoglobin distribution but recent innovative developments in hyperspectral technology may offer a solution. We examined different hemodynamic disorders in patients suffering from scleroderma, Dupuytren surgery, chronic foot ulcera and skin infections. Superficial and deeper blood oxygen saturation, hemoglobin distribution and water content were determined using hyperspectral imaging (HSI). In the patient with scleroderma, distinct cutaneous low perfused regions correlated with macroscopic skin aspects and seem to be potential therapy control marker. With HSI accurate clinical evaluation of a macroscopic conspicuous wound after Dupuytren surgery was possible and influenced further surveillance decisions. HSI clearly revealed the spatial geometry and also the clinically related perfusion parameters of abscess formation and chronic ulcer wounds. The hemodynamically relevant parameters like blood oxygen saturation (1 mm to approx. 6 mm subcutaneous), total hemoglobin distribution and tissue water content can be easily determined and visualized with HSI in near real time. Hence, this technique seems to be suitable for routine diagnostics of acute and chronic wounds as well as for the examination of systemic hemodynamic disturbances. Special indications may be transplant surveillance and monitoring of therapeutical interventions. |
| Databáze: | OpenAIRE |
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