A minimally invasive microdevice for molecular sampling and analysis
| Autor: | P. Caillat, François Berger, Ali Bouamrani, F. Martin, M. Cosnier |
|---|---|
| Přispěvatelé: | Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), 'Canceropole Lyon Auvergne Rhone Alpes' Nanobio innovation pole, Issartel, Jean-Paul |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Computer science
Biopsy Biomedical Engineering Oncological surgery MESH: Equipment Failure Analysis Nanotechnology 01 natural sciences Sensitivity and Specificity 03 medical and health sciences MESH: Biopsy Biopolymers Biopsy device Tissue damage medicine Microtechnology Minimally Invasive Surgical Procedures 030304 developmental biology [SDV.IB] Life Sciences [q-bio]/Bioengineering 0303 health sciences Miniaturization medicine.diagnostic_test 010401 analytical chemistry Cancer Reproducibility of Results MESH: Computer-Aided Design Equipment Design MESH: Miniaturization medicine.disease Microarray Analysis MESH: Sensitivity and Specificity 3. Good health 0104 chemical sciences Molecular analysis Equipment Failure Analysis MESH: Reproducibility of Results MESH: Biopolymers MESH: Microarray Analysis Tissue Array Analysis Chemical functionalization Computer-Aided Design MESH: Surgical Procedures Minimally Invasive [SDV.IB]Life Sciences [q-bio]/Bioengineering MESH: Tissue Array Analysis Biomedical engineering MESH: Equipment Design |
| Zdroj: | IEEE Transactions on Biomedical Engineering IEEE Transactions on Biomedical Engineering, Institute of Electrical and Electronics Engineers, 2009, 56 (12), pp.2898-904. ⟨10.1109/TBME.2009.2026582⟩ IEEE Transactions on Biomedical Engineering, 2009, 56 (12), pp.2898-904. ⟨10.1109/TBME.2009.2026582⟩ |
| ISSN: | 0018-9294 |
| DOI: | 10.1109/TBME.2009.2026582⟩ |
| Popis: | International audience; In this paper, we present a new minimally invasive biopsy microdevice adapted to proteomic mass spectrometry analysis. The concept is born from a multidisciplinary collaboration in fields of proteomics, cancer research, and microtechnology. In mixing different skills, we have developed and manufactured a miniaturized biopsy device using microtechnology techniques in order to minimize tissue damage during surgical gesture. Dedicated chemically functionalized areas were added to the device in order to increase capture yield and specificity during tissue contact. Fields of application range from cancer research to the study of neurodegenerative diseases. |
| Databáze: | OpenAIRE |
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