Correlates of the discrepancy between objective and subjective cognitive functioning in non-demented patients with Parkinson's disease
| Autor: | Mattia Siciliano, Alfonso Giordano, Antonio Russo, Carlo Chiorri, Gioacchino Tedeschi, Rosa De Micco, L. Trojano, Luca Passamonti, Valeria Sant'Elia, Alessandro Tessitore |
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| Přispěvatelé: | Passamonti, Luca [0000-0002-7937-0615], Apollo - University of Cambridge Repository, Siciliano, M., Trojano, L., De Micco, R., Sant'Elia, V., Giordano, A., Russo, A., Passamonti, L., Tedeschi, G., Chiorri, C., Tessitore, A. |
| Rok vydání: | 2021 |
| Předmět: |
Parkinson's disease
Neuropsychological Tests Logistic regression 050105 experimental psychology 03 medical and health sciences 0302 clinical medicine Cognition Cognitive impairment Depression Fatigue Mild cognitive impairment Subjective cognitive decline Rating scale medicine Humans 0501 psychology and cognitive sciences Cognitive Dysfunction Cognitive skill Depression (differential diagnoses) Psychiatric Status Rating Scales Original Communication business.industry 05 social sciences Beck Depression Inventory Montreal Cognitive Assessment Parkinson Disease medicine.disease Neurology Neurology (clinical) business Cognition Disorders 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Journal of neurology 268 (2021): 3444–3455. doi:10.1007/s00415-021-10519-4 info:cnr-pdr/source/autori:Siciliano M.; Trojano L.; De Micco R.; Sant'Elia V.; Giordano A.; Russo A.; Passamonti L.; Tedeschi G.; Chiorri C.; Tessitore A./titolo:Correlates of the discrepancy between objective and subjective cognitive functioning in non-demented patients with Parkinson's disease/doi:10.1007%2Fs00415-021-10519-4/rivista:Journal of neurology (Print)/anno:2021/pagina_da:3444/pagina_a:3455/intervallo_pagine:3444–3455/volume:268 Journal of Neurology |
| DOI: | 10.1007/s00415-021-10519-4 |
| Popis: | Background Subjective complaints of cognitive deficits are not necessarily consistent with objective evidence of cognitive impairment in Parkinson’s disease (PD). Here we examined the factors associated with the objective-subjective cognitive discrepancy. Methods We consecutively enrolled 90 non-demented patients with PD who completed the Parkinson’s Disease Cognitive Functional Rating Scale (subjective cognitive measure) and the Montreal Cognitive Assessment (MoCA; objective cognitive measure). The patients were classified as “Overestimators”, “Accurate estimators”, and “Underestimators” on the basis of the discrepancy between the objective vs. subjective cognitive measures. To identify the factors distinguishing these groups from each other, we used chi-square tests or one-way analyses of variance, completed by logistic and linear regression analyses. Results Forty-nine patients (54.45%) were classified as “Accurate estimators”, 29 (32.22%) as “Underestimators”, and 12 (13.33%) as “Overestimators”. Relative to the other groups, the “Underestimators” scored higher on the Fatigue Severity Scale (FSS), Beck Depression Inventory (BDI), and Parkinson Anxiety Scale (p p p p Conclusion In more than 45% of consecutive non-demented patients with PD, we found a ‘mismatch’ between objective and subjective measures of cognitive functioning. Such discrepancy, which was related to the presence of fatigue and depressive symptoms and frontal executive impairments, should be carefully evaluated in clinical setting. |
| Databáze: | OpenAIRE |
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