Impact of Routine Use of Drug-eluting Stents in Contemporary Interventional Cardiology at a Tertiary Center: One-decade Experience of the DESIRE Registry
| Autor: | Amanda G. M. R. Sousa, J. Ribamar Costa Junior, J. Eduardo Sousa, Manuel Cano, Adriana Moreira, Galo Maldonado, Cantídio Campos Neto, Ricardo A. Costa |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Angioplastia medicine.medical_treatment Revascularization Stents farmacológicos Doenga das coronárias Angioplasty medicine Myocardial infarction Stent thrombosis Registries Drug-eluting stents Coronary disease Interventional cardiology business.industry General surgery Percutaneous coronary intervention Mean age General Medicine medicine.disease Surgery Conventional PCI Sistema de registros business Cardiology and Cardiovascular Medicine |
| Zdroj: | Revista Brasileira de Cardiologia Invasiva English Version. 20(4):355-360 |
| ISSN: | 0104-1843 |
| DOI: | 10.1016/s0104-1843(12)50060-3 |
| Popis: | Background Drug-eluting stents (DES) have changed contemporary interventional cardiology practice, enabling the approach of increasingly more complex clinical and angiographic scenarios. The objective of this study was to demonstrate the changes observed in the last 10 years in the indication and practice of percutaneous coronary intervention (PCI) at a tertiary private hospital in the State of Sao Paulo. Methods DESIRE is a single-center prospective registry aiming at following the acute and late outcomes of consecutive patients treated by DES. Results From 2002 to 2011, 4,299 patients were included, with mean age of 64.3 ± 11.2 years, 23% were female and 30.5 were diabetic. The total number of lesions treated was 6,518 of which 61.5% were type B2/C. During the course of the study, DES were progressively more used, reaching a penetration of 88.4% in 2011. The complexity of PCIs has increased and in the past year 1.76 lesions per patient were treated with an average of 1.89 DES. The SYNTAX score increased from 12.3 ± 4.4 (2002-2006) to 15.7 ± 4.7 (2007-2011). Clinical follow-up was obtained in 98.2% of the patients, with a median of 5.2 years, and during this period target-lesion revascularization rate was 5%, myocardial infarction was 6.7% and cardiovascular death was 4.1%. Stent thrombosis was observed in 2.4% of the cases. Conclusions Our results showed a marked increment in the complexity profile of patients treated in the last 10 years and at the same time confirm the long-term effectiveness of DES, despite the clinical and angiographic profile of patients. |
| Databáze: | OpenAIRE |
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