Effect of ascorbic acid on urinary hydroxyproline of children receiving corticosteroids
| Autor: | Ch. Coulouris, D. Liakakos, K. Ntalles, D. Ikkos, P. Vlachos |
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| Rok vydání: | 1974 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Prednisolone Urinary system Ascorbic Acid Bone and Bones Excretion Collagen formation Hydroxyproline chemistry.chemical_compound Oral administration Internal medicine medicine Humans Child business.industry Mean value Original Articles Ascorbic acid Endocrinology chemistry Pediatrics Perinatology and Child Health Female Collagen Rheumatic Fever business medicine.drug |
| Zdroj: | Archives of Disease in Childhood. 49:400-403 |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/adc.49.5.400 |
| Popis: | Oral administration of ascorbic acid, 0·5 g every 8 hours for a period of 4 days, had no effect on the urinary hydroxyproline excretion of 7 healthy children aged 8 to 14 years. When the same medication was given to 8 children aged 9 to 14 years who were receiving large doses of prednisolone (2 mg/kg per 24 hr) for a period of at least 15 days before as well as during ascorbic acid administration, a rise in the urinary hydroxyproline excretion was observed (from a mean value of 44±4·1 SE before to 67±4·6 mg/24 hr on the 4th day of ascorbic acid administration, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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