Immunocytochemical studies of cell differentiation during rat salivary gland development
Autor: | Lily Mirels, Savithri Sivakumar, Arthur R. Hand, William D. Ball, Ivan Barta |
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Rok vydání: | 1996 |
Předmět: |
Transition (genetics)
Cellular differentiation Submandibular Gland Rat Salivary Gland Cell Differentiation Biology Immunohistochemistry Agricultural and Biological Sciences (miscellaneous) Phenotype Cell biology Secretory protein stomatognathic system biology.protein Animals Parotid Gland Anatomy Antibody Biomarkers |
Zdroj: | European Journal of Morphology. 34:149-154 |
ISSN: | 0924-3860 |
DOI: | 10.1076/ejom.34.3.149.13032 |
Popis: | The development of the rat submandibular and parotid glands has been studied using antibodies to secretory proteins as cell-specific markers. Although the morphology of the glands and the timing of the main steps of cytodifferentiation are substantially different, they have several proteins and developmental features in common. The latter include the initial formation of perinatal acini which undergo a transition to adult acini expressing a different complement of secretory proteins; the development of adult intercalated ducts (ID) from the perinatal acinar cells; and the retention of the perinatal phenotype in some cells of the ID. |
Databáze: | OpenAIRE |
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