Antitumor and immunomodulating activities of six Phellinus igniarius polysaccharides of different origins
| Autor: | Shu-wen Yu, Wenjian Sun, Mingfang Wang, Wenwen Gao, Wangdi Wang, Na Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cancer Research Phellinus igniarius polysaccharides Spleen immunomodulation 03 medical and health sciences 0302 clinical medicine Immune system Immunology and Microbiology (miscellaneous) In vivo medicine MTT assay Cytotoxicity Phellinus igniarius antitumor biology spleen and thymus index General Medicine Articles biology.organism_classification Molecular biology In vitro cytokines 030104 developmental biology medicine.anatomical_structure Apoptosis 030220 oncology & carcinogenesis |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| Popis: | The aim of the current study was to compare the antitumor efficiency of Phellinus igniarius polysaccharides (PIP) from six different origins and preliminarily investigate its potential mechanisms. PIP was extracted using the microwave extraction method. The corresponding in vivo antitumor efficacy was assessed in Kunming mice bearing H22 tumors and Gansu PIP (GPIP) was identified to have a significantly higher antitumor efficacy compared with the control group (P0.05). The spleen index of the GPIP group significantly increased compared with the saline and CTX groups (P |
| Databáze: | OpenAIRE |
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