Enrichment of Food With Tannin Extracts Promotes Healthy Changes in the Human Gut Microbiota
| Autor: | Silvia Molino, Alberto Lerma-Aguilera, Nuria Jiménez-Hernández, María José Gosalbes, José Ángel Rufián-Henares, M. Pilar Francino |
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| Přispěvatelé: | [Molino,S, Rufián-Henares,JA] Departamento de Nutrición y Bromatología, Instituto de Nutrición y Tecnología de los Alimentos, Centro de Investigación Biomédica, Universidad de Granada, Granada, Spain. [Lerma-Aguilera,A, Jiménez-Hernández,N, Gosalbés,MJ, Francino,M] Area de Genòmica i Salut, Fundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana (FISABIO-Salut Pública), València, Spain. [Jiménez-Hernández,N, Francino,M] CIBER en Epidemiología y Salud Pública, Madrid, Spain. [Rufián-Henares,JA] Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain., This work was supported by the research project Stance4Health (contract no. 816303) from the European Commission (Research Executive Agency) |
| Rok vydání: | 2021 |
| Předmět: |
Taninos
Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Carbohydrate Metabolism::Fermentation [Medical Subject Headings] Food industry chestnut 030309 nutrition & dietetics lcsh:QR1-502 in vitro digestion-fermentation Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::RNA::RNA Ribosomal::RNA Ribosomal 16S [Medical Subject Headings] Gut flora lcsh:Microbiology Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Tannins [Medical Subject Headings] Tannin Food science Original Research 2. Zero hunger chemistry.chemical_classification 0303 health sciences digestive oral and skin physiology Short chain fatty acids Technology and Food and Beverages::Technology Industry and Agriculture::Industry::Food Industry [Medical Subject Headings] 3. Good health Composition (visual arts) Ruminococcaceae Microbiology (medical) Microbioma gastrointestinal quebracho Aesculus Gut microbiota Biology digestive system Microbiology 03 medical and health sciences Human gut tannins Persons::Persons::Volunteers::Healthy Volunteers [Medical Subject Headings] Chestnut 030304 developmental biology Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Volatile [Medical Subject Headings] gut microbiota business.industry Ácidos grasos volátiles Lachnospiraceae biology.organism_classification Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutrition Processes::Digestion [Medical Subject Headings] tara Technology and Food and Beverages::Food and Beverages::Food::Micronutrients [Medical Subject Headings] Chemicals and Drugs::Complex Mixtures::Biological Products::Plant Preparations::Plant Extracts [Medical Subject Headings] chemistry In vitro digestion–fermentation Quebracho Fermentation Tara business short chain fatty acids Tannins |
| Zdroj: | Frontiers in Microbiology, Vol 12 (2021) Digibug. Repositorio Institucional de la Universidad de Granada instname Frontiers in Microbiology Digibug: Repositorio Institucional de la Universidad de Granada Universidad de Granada (UGR) |
| ISSN: | 1664-302X |
| DOI: | 10.3389/fmicb.2021.625782 |
| Popis: | This work was supported by the research project Stance4Health (contract no. 816303) from the European Commission (Research Executive Agency). The sequence data are available in the European Nucleotide Archive (ENA) under accession number PRJEB14013 (https:// www.ebi.ac.uk/ena/browser/view/PRJEB41013). This paper will form part of the doctoral thesis of SM, conducted within the context of the “Nutrition and Food Sciences Programme” at the University of Granada The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmicb.2021.625782/ full#supplementary-material Food and food bioactive components are major drivers of modulation of the human gut microbiota. Tannin extracts consist of a mix of bioactive compounds, which are already exploited in the food industry for their chemical and sensorial properties. The aim of our study was to explore the viability of associations between tannin wood extracts of different origin and food as gut microbiota modulators. 16S rRNA amplicon next-generation sequencing (NGS) was used to test the effects on the gut microbiota of tannin extracts from quebracho, chestnut, and tara associated with commercial food products with different composition in macronutrients. The different tannin-enriched and non-enriched foods were submitted to in vitro digestion and fermentation by the gut microbiota of healthy subjects. The profile of the short chain fatty acids (SCFAs) produced by the microbiota was also investigated. The presence of tannin extracts in food promoted an increase of the relative abundance of the genus Akkermansia, recognized as a marker of a healthy gut, and of various members of the Lachnospiraceae and Ruminococcaceae families, involved in SCFA production. The enrichment of foods with tannin extracts had a booster effect on the production of SCFAs, without altering the profile given by the foods alone. These preliminary results suggest a positive modulation of the gut microbiota with potential benefits for human health through the enrichment of foods with tannin extracts. European Commission European Commission Joint Research Centre 816303 |
| Databáze: | OpenAIRE |
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