Laparoscopic pancreaticoduodenectomy for adenocarcinoma provides short-term oncologic outcomes and long-term overall survival rates similar to those for open pancreaticoduodenectomy
| Autor: | David J. Winchester, Olga Kantor, David J. Bentrem, Richard A. Prinz, Kevin K. Roggin, Waseem Lutfi, Susan M. Sharpe, Marshall S. Baker, Mark S. Talamonti |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Databases Factual medicine.medical_treatment Adenocarcinoma 030230 surgery Patient Readmission Gastroenterology Pancreaticoduodenectomy 03 medical and health sciences 0302 clinical medicine Hospital volume hemic and lymphatic diseases Internal medicine medicine Overall survival Humans Stage (cooking) Aged Retrospective Studies business.industry General Medicine Length of Stay medicine.disease United States Cancer data Surgery Pancreatic Neoplasms Chemotherapy Adjuvant 030220 oncology & carcinogenesis Multivariate Analysis Female Laparoscopy business Laparoscopic pancreaticoduodenectomy |
| Zdroj: | The American Journal of Surgery. 213:512-515 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2016.10.030 |
| Popis: | The long-term efficacy of laparoscopic pancreaticoduodenectomy (LPD) relative to open pancreaticoduodenectomy (OPD) for pancreatic adenocarcinoma has not been well studied.The National Cancer Data Base was used to compare patients undergoing LPD and OPD for stage I-II pancreatic adenocarcinoma between 2010 and 2013.828 (10%) patients underwent LPD and 7385 (90%) OPD. There were no differences in tumor or demographic characteristics between groups. On multivariable analysis adjusted for hospital volume, LPD was associated with a lower rate of readmission (p 0.01) and trends toward shorter initial length of stay (p = 0.14) and time to adjuvant chemotherapy (p = 0.11). There were no differences between patients undergoing LPD and those undergoing OP in rates of margin negative resection, number of lymph nodes examined, perioperative mortality and median overall survival (20.7 vs 20.9 months, p = 0.68).For patients with localized pancreatic adenocarcinoma, LPD provides short-term oncologic and long-term overall survival outcomes identical to OPD and is associated with decreased rates of readmission and a trend towards accelerated recovery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect