Near infrared spectroscopy (NIRS): a new tool to study hemodynamic changes during activation of brain function in human adults
| Autor: | L. Schleinkofer, Christoph Hock, J. Planck, Arno Villringer, Ulrich Dirnagl |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Frontal cortex Spectrophotometry Infrared Hemodynamics Stimulation Hemoglobins Nuclear magnetic resonance Cognition Cortex (anatomy) medicine Laser-Doppler Flowmetry Deoxygenated Hemoglobin Humans Brain function Skin Cerebral Cortex Oxygenated Hemoglobin Blood Volume Chemistry General Neuroscience Near-infrared spectroscopy medicine.anatomical_structure Regional Blood Flow Cerebrovascular Circulation Female Occipital Lobe Neuroscience Photic Stimulation |
| Zdroj: | Neuroscience letters. 154(1-2) |
| ISSN: | 0304-3940 |
| Popis: | In healthy human adults, cerebral concentrations of oxygenated hemoglobin ([HbO2]) and deoxygenated hemoglobin ([HbR]) were assessed during brain activation using near infrared spectroscopy (NIRS). Measurements were made either in the frontal cortex (n = 10) during performance of cognitive tasks or in the occipital cortex (n = 6) during visual stimulation (flash-light exposure, picture observation). The typical findings during brain activation were an increase in [HbO2] and a decrease in [HbR]. We demonstrate that these findings are not due to alterations in skin blood flow. NIRS is a simple bedside technique for the assessment of hemodynamic alterations accompanying brain activation. |
| Databáze: | OpenAIRE |
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