Patterns of pulmonary tuberculosis on FDG-PET/CT
| Autor: | Pierre-Yves Brillet, Michel Brauner, Patrick Nicolas, Abrahim Khafagy, Michael Soussan, Annie Vessieres, Arsène Mekinian |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Multimodal Imaging Sensitivity and Specificity Mycobacterium tuberculosis Fluorodeoxyglucose F18 Pulmonary tuberculosis Parenchyma medicine Humans Radiology Nuclear Medicine and imaging Tuberculosis Pulmonary Aged Aged 80 and over Lung biology business.industry Reproducibility of Results General Medicine Middle Aged biology.organism_classification medicine.disease medicine.anatomical_structure Lymphatic system Positron-Emission Tomography Female Fdg pet ct Lymph Radiology Radiopharmaceuticals Tomography X-Ray Computed business |
| Zdroj: | European Journal of Radiology. 81:2872-2876 |
| ISSN: | 0720-048X |
| Popis: | Objective This study aims to describe patterns of pulmonary tuberculosis (TB) on FDG-PET/CT. Methods All patients with a diagnosis of TB and who underwent FDG-PET/CT between January 2009 and June 2010 were included. Clinical, biological and imaging data were reviewed. TB was proven either on bacteriological or histopathological studies (n = 13) or on a clinical and imaging basis (n = 3). Results Sixteen patients (11 men; median age 56, range 22–84 years) were included. Two distinct patterns were identified. In the lung pattern (9/16), patients had predominantly pulmonary symptoms (6/9 patients, 67%) with a parenchymal involvement: uptakes on lung consolidation ± cavitation surrounded by micronodules. Mediastino-hilar lymph nodes were slightly enlarged (15 mm, 10–27) with moderate uptake (3.9, 2.5–13.4). In the lymphatic pattern (7/16), patients had predominantly systemic symptoms (5/7 cases, 71%) and all had extra-thoracic involvement. Mediastino-hilar lymph nodes were more enlarged (30 mm, 18–35, p = 0.03) and with higher uptake (6.8, 5.7–16.8, p = 0.034) than in the lung pattern. Conclusion We identified two distinct patterns of pulmonary TB on FDG-PET/CT. The lung pattern related to a restricted and slight hypermetabolic infection and the lymphatic pattern related to a systemic and intense infection. Combined interpretation of PET and CT findings improves the specificity of images, especially for the lung pattern. |
| Databáze: | OpenAIRE |
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