The effect of green kiwifruit on gas transit and tolerance in healthy humans

Autor: Bouchra Benslaiman, Noemí Caballero, Jordi Serra, Juliet Ansell
Rok vydání: 2020
Předmět:
Zdroj: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Neurogastroenterology and Motility
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
ISSN: 1350-1925
Popis: Background Green kiwifruit is a fiber‐rich fruit that has been shown effective for treatment of constipation. However, fermentation of fibers by colonic bacteria may worsen commonly associated gas‐related abdominal symptoms. Aim: To determine the effect of green kiwifruit on transit and tolerance to intestinal gas in humans. Methods In 11 healthy individuals, two gas challenge tests were performed (a) after 2 weeks on a low‐flatulogenic diet and daily intake of 2 green kiwifruits and (b) after 2 weeks on a similar diet without intake of kiwifruits. The gas challenge test consisted in continuous infusion of a mixture of gases into the jejunum at 12 mL/min for 2 hours while measuring rectal gas evacuation, abdominal symptoms, and abdominal distension. During the 2 weeks prior to each gas challenge test (on‐kiwifruit and off‐kiwifruit), the number and consistency of stools, and abdominal symptoms were registered. Key Results Intake of kiwifruits was associated with more bowel movements per day (1.8 ± 0.1 vs 1.5 ± 0.1 off‐kiwifruit; P = .001) and somewhat looser stools (Bristol score 3.3 ± 0.2 vs 2.8 ± 0.1 off‐kiwifruit; P = .072) without relevant abdominal symptoms. Gas infusion produced similar gas evacuation (1238 ± 254 mL and 1172 ± 290 mL; P = .4355), perception of symptoms (score 1.2 ± 0.2 and 1.3 ± 0.3; P = .2367), and abdominal distension (17 ± 7 mm and 17 ± 6 mm; P = .4704) while on‐kiwifruit or off‐kiwifruit. Conclusions and Inferences In healthy subjects, green kiwifruit increases stool frequency without relevant effects on intestinal gas transit and tolerance. If confirmed in patients, these fruits may provide a natural and well‐tolerated treatment alternative for constipation.
In a cross‐over, randomized study in healthy subjects, intake of the fibre‐rich green kiwifruit increased bowel movements without effects on gas transit and tolerance in response to a gas challenge test. If confirmed in patients, these fruits may provide a natural and well tolerated treatment alternative for constipation.
Databáze: OpenAIRE
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