The Mediating Role of Depressive Symptoms in the Association Between Food Insecurity and HIV Related Health Outcomes Among HIV–HCV Co-Infected People
| Autor: | Wusiman Aibibula, Paul Brassard, Marina B. Klein, Joseph Cox, Anne-Marie Hamelin |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Canada medicine.medical_specialty Sustained Virologic Response Social Psychology Psychological intervention HIV Infections Food Supply Medication Adherence 03 medical and health sciences 0302 clinical medicine Antiretroviral Therapy Highly Active Environmental health Outcome Assessment Health Care Humans Medicine 030212 general & internal medicine Association (psychology) 030505 public health Food security Coinfection Depression business.industry Public health Public Health Environmental and Occupational Health Viral Load Hepatitis C Food insecurity Health psychology Infectious Diseases Anti-Retroviral Agents Cohort Female 0305 other medical science business Viral load |
| Zdroj: | AIDS and Behavior. 24:2188-2194 |
| ISSN: | 1573-3254 1090-7165 |
| DOI: | 10.1007/s10461-020-02784-7 |
| Popis: | Food insecurity may lead to depressive symptoms, which are known to be associated with poor HIV related health outcomes. However, it is unclear to what extent food insecurity 'directly' affects these outcomes. We used data from the Food Security & HIV-HCV Sub-Study of the Canadian Co-Infection Cohort to assess the controlled direct effect. People experiencing severe food insecurity had 1.47 (95% CI 1.04-2.09) times the risk of having detectable HIV viral load and 0.94 (95% CI 0.87-1.02) fold change in CD4 count. After holding depressive symptoms constant, the association between severe food insecurity and HIV viral load was attenuated to a statistically non-significant level (RR 1.36, 95% CI: 0.95-1.96), whereas the association between severe food insecurity and CD4 count was unchanged. Depressive symptoms partially mediate the effect of severe food insecurity on HIV viral suppression; interventions focused on depressive symptoms alone may not be sufficient, however, to eliminate this effect. |
| Databáze: | OpenAIRE |
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