Effects of NO2 exposure on daily mortality in São Paulo, Brazil
| Autor: | Costa, Amine Farias, Hoek, Gerard, Brunekreef, Bert, Ponce de Leon, Antonio Carlos Monteiro, dIRAS RA-2, LS IRAS EEPI ME (Milieu epidemiologie), dIRAS RA-I&I RA |
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| Přispěvatelé: | dIRAS RA-2, LS IRAS EEPI ME (Milieu epidemiologie), dIRAS RA-I&I RA |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
010504 meteorology & atmospheric sciences Meteorology Nitrogen Dioxide Air pollution 010501 environmental sciences medicine.disease_cause Research Support 01 natural sciences Biochemistry complex mixtures chemistry.chemical_compound Human health Ozone Environmental health 80 and over Medicine Humans Nitrogen dioxide Particle Size Non-U.S. Gov't 0105 earth and related environmental sciences General Environmental Science Aged Pollutant Aged 80 and over Air Pollutants Carbon Monoxide business.industry Research Support Non-U.S. Gov't Generalized additive model Environmental exposure Environmental Exposure Particulates Middle Aged Cumulative risk chemistry Cardiovascular Diseases Female Particulate Matter business Brazil |
| Zdroj: | Environmental Research, 159, 539. Academic Press Inc. |
| ISSN: | 0013-9351 |
| Popis: | Background Recent reports have suggested that air pollution mixtures represented by nitrogen dioxide (NO2) may have effects on human health, which are independent from those of particulate matter mass. We evaluate the association between NO2 and daily mortality among elderly using one- and multipollutant models. Methods This study was a daily time series of non-accidental and cause-specific mortality among the elderly living in Sao Paulo, Brazil, between 2000 and 2011. Effects of NO2, particulate matter smaller than 10 µm (PM10), carbon monoxide (CO) and ozone (O3) were estimated in Poisson generalized additive models. The single lag effect at lags 0 and 1 days and the cumulative effect from 0 to lag 10 days were evaluated in one-, two-, three- and four-pollutant models. The cumulative risk index (CRI) recently proposed to analyze associations with health of multiple correlated pollutants was additionally estimated for each multipollutant model. Results An association between NO2, PM10, CO and O3 exposures and non-accidental and cause-specific deaths was found in one-pollutant models. NO2 effects remained significant in multipollutant models for non-accidental and circulatory deaths. The estimated CRIs suggested that circulatory deaths were mainly associated with NO2, and respiratory deaths mainly with CO and O3, regardless the lag. For non-accidental deaths, multipollutant models were associated with the highest CRI, with the main pollutants depending on the chosen lag. Conclusions The results suggest that air pollution mixtures represented by NO2 have an effect on non-accidental and circulatory mortality, which is independent from PM10, CO and O3. The CRI was always larger than the risks associated with single pollutants. |
| Databáze: | OpenAIRE |
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