Knocking Down Gene Expression with Dendritic Vectors
| Autor: | Patrizia Paolicelli, Manuela Raviña, Alejandro Sánchez, Begoña Seijo |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pharmacology
Regulation of gene expression Dendrimers Dendritic Polymers Nanotechnology DNA Catalytic Genetic Therapy General Medicine Computational biology Oligonucleotides Antisense Biology Genetic therapy Antisense Elements (Genetics) Gene Expression Regulation RNA interference Gene Knockdown Techniques Drug Discovery Gene expression Animals Humans RNA Interference RNA Catalytic RNA Small Interfering |
| Zdroj: | Mini-Reviews in Medicinal Chemistry. 10:73-86 |
| ISSN: | 1389-5575 |
| Popis: | The aim of this review is to provide the reader with an overview on the potential of dendritic polymers in the antisense delivery technology. Special emphasis has been placed on the different types of dendritic structures that have been reported and the modifications performed to increase their efficacy and safety. Therefore the advances made in their chemistry and how it has been adapted to meet the specific requirements of the antisense delivery technology are reviewed and discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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