Development and an initial validation of the Responses to Illness Severity Quantification (RISQ) score for severely malnourished children

Autor: Nancy M. Dale, Garba Mohammed Ashir, Lawan Bukar Maryah, Susan Shepherd, George Tomlinson, André Briend, Stanley Zlotkin, Christopher Parshuram
Přispěvatelé: Tampere University, Clinical Medicine
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Dale, N M, Ashir, G M, Maryah, L B, Shepherd, S, Tomlinson, G, Briend, A, Zlotkin, S & Parshuram, C 2022, ' Development and an initial validation of the Responses to Illness Severity Quantification (RISQ) score for severely malnourished children ', Acta Pædiatrica, vol. 111, no. 9, pp. 1752-1763 . https://doi.org/10.1111/apa.16410
DOI: 10.1111/apa.16410
Popis: Aim: To develop and perform an initial validation of a score to measure severity of illness in hospitalized children with severe acute malnutrition (SAM).Methods: A prospective study enrolled SAM children aged 6-59 months hospitalized in Borno State, Nigeria. Candidate items associated with inpatient mortality were combined and evaluated as candidate scores. Clinical and statistical methods were used to identify a preferred score.Results: The 513 children enrolled had a mean age of 15.6 months of whom 48 (9%) died. Seven of the ten evaluated items were significantly associated with mortality. Five different candidate scores were tested. The final score, Responses to Illness Severity Quantification (RISQ), included 7 items: heart rate, respiratory rate, respiratory effort, oxygen saturation, oxygen delivery, temperature and level of consciousness. The mean RISQ score on admission was 2.6 in hospital survivors and 7.3 for children dying Conclusion: The RISQ score can identify high risk malnourished children at and during hospital admission. Clinical application may help prioritize care and potentially improve survival.
Databáze: OpenAIRE
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