Age and Mortality in Pediatric Severe Traumatic Brain Injury: Results from an International Study
Autor: | Ajit, Sarnaik, Nikki Miller, Ferguson, A M Iqbal, O'Meara, Shruti, Agrawal, Akash, Deep, Sandra, Buttram, Michael J, Bell, Stephen R, Wisniewski, James F, Luther, Adam L, Hartman, Monica S, Vavilala |
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Rok vydání: | 2018 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Comparative Effectiveness Research Adolescent Traumatic brain injury Poison control Critical Care and Intensive Care Medicine Severity of Illness Index Cohort Studies 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Injury prevention Brain Injuries Traumatic medicine Humans Child business.industry Incidence (epidemiology) Confounding Glasgow Coma Scale Age Factors medicine.disease Child Preschool Cohort Female Neurology (clinical) business 030217 neurology & neurosurgery Cohort study |
Zdroj: | Neurocritical care. 28(3) |
ISSN: | 1556-0961 |
Popis: | Although small series have suggested that younger age is associated with less favorable outcome after severe traumatic brain injury (TBI), confounders and biases have limited our understanding of this relationship. We hypothesized that there would be an association between age and mortality in children within an ongoing observational, cohort study. The first 200 subjects from the Approaches and Decisions for Acute Pediatric TBI trial were eligible for this analysis (inclusion criteria: severe TBI (Glasgow Coma Scale [GCS] score ≤ 8], age 18 years, and intracranial pressure (ICP) monitor placed; exclusion: pregnancy). Children with suspected abusive head trauma (AHT) were excluded to avoid bias related to the association between AHT and mortality. Demographics, and prehospital and resuscitation events were collected/analyzed, and children were stratified based on age at time of injury ( |
Databáze: | OpenAIRE |
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