What is the effect of resveratrol on obesity? A systematic review and meta-analysis
| Autor: | Gicele Costa Mintem, Lílian Munhoz Figueiredo, Eduardo Lucia Caputo, Felipe Mendes Delpino, Denise Petrucci Gigante |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Waist Endocrinology Diabetes and Metabolism Population 030209 endocrinology & metabolism Overweight Resveratrol Body Mass Index 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Weight loss Internal medicine medicine Humans Obesity education education.field_of_study 030109 nutrition & dietetics Nutrition and Dietetics business.industry Body Weight medicine.disease chemistry Meta-analysis medicine.symptom business Body mass index |
| Zdroj: | Clinical Nutrition ESPEN. 41:59-67 |
| ISSN: | 2405-4577 |
| DOI: | 10.1016/j.clnesp.2020.11.025 |
| Popis: | Summary Background & aims Obesity is increasing worldwide. Resveratrol appears as a substance capable of helping with weight loss. This study aimed to investigate the resveratrol effect in the treatment of obesity in general population. Methods An online search was conducted in the following databases: Pubmed, LILACS, Scielo, Scopus and Web of Science. Experimental studies that investigated the effects between resveratrol supplementation for weight loss treatment, as well as its relationship with overweight and obesity were included. Observational and non-human studies were excluded. The Cochrane scale was used to assess the quality of the studies. Results Nineteen studies were included, of which only three demonstrated some type of positive effect. In the meta-analysis, there was no significant effect on weight loss [SMD: 0.03; CI95%: −0,44, 0,49; p = 0,01; I2 = 82%], and body mass index (BMI) [SMD: 0.01; CI95%: −0,39, 0,41; p = 0,01; I2 = 72%]. A small effect was found on the waist circumference [SMD: −1.04; CI95%: −1,86, −0,27; p = 0,01; I2 = 87%]. Conclusion This systematic review with meta-analysis demonstrated that supplementation with resveratrol does not have an anti-obesity effect. |
| Databáze: | OpenAIRE |
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