Hyperinsulinemia in Patients with Spastic Angina Pectoris
| Autor: | Ryuichiro Miyawaki, Kazuo Moroe, Kei Miyoshi, Yoshio Urabe, Tadayuki Hiroki, Tetsushi Wakiyama, Takayuki Furuki |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Angina Pectoris
Variant Blood Glucose Male medicine.medical_specialty medicine.medical_treatment Coronary Artery Disease Coronary Angiography Body Mass Index Diagnosis Differential Angina Impaired glucose tolerance Hyperinsulinism Internal medicine medicine Hyperinsulinemia Spastic Humans Insulin Pharmacology (medical) Angina Unstable cardiovascular diseases Risk factor Triglycerides business.industry Cholesterol HDL Glucose Tolerance Test Middle Aged medicine.disease Acetylcholine nervous system diseases Surgery Cholesterol Coronary vasospasm Cohort Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiology. 88:503-508 |
| ISSN: | 1421-9751 0008-6312 |
| DOI: | 10.1159/000177399 |
| Popis: | We evaluated the association between coronary spasm and hyperinsulinemia (high immunoreactive insulin, IRI) in patients with angina pectoris. The study cohort comprised 30 patients with spastic angina pectoris, 30 patients with angina pectoris showing fixed-obstructive coronary sclerosis and 30 control subjects who were matched for body mass index, age and sex. A 75-gram oral glucose test was performed, and blood sugar and IRI were serially measured concomitant with serum total cholesterol, triglyceride and HDL cholesterol. The IRI level at 60 min, the peak IRI during the test, sigma IRI and sigma IRI/sigma blood sugar were significantly higher in the patients than in the controls. Total cholesterol and LDL cholesterol levels were significantly increased in patients showing fixed-obstructive coronary sclerosis compared to controls. |
| Databáze: | OpenAIRE |
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