Preparation and characterization of Tegafur magnetic thermosensitive liposomes

Autor: Yang-de Zhang, Liu Xingyan, Xiao-li Wang, Zhao-wu Zeng, Nianfeng Li, Wei-hua Zhou
Rok vydání: 2009
Předmět:
Zdroj: Pharmaceutical Development and Technology. 14:350-357
ISSN: 1097-9867
1083-7450
DOI: 10.1080/10837450802647300
Popis: The purpose was to study the preparation and properties of tegafur magnetic thermosensitive liposomes. The method was to employ an improved chemical coprecipitation method for preparing nano-magnetic particles and a reverse-phase evaporation and ultrasonic method for preparing tegafur magnetic thermosensitive liposomes. The results showed that tegafur magnetic thermosensitive liposomes were prepared successfully. They had comparatively strong magnetism and superparamagnetism, and their temperature showed a linear positive correlation with dosages and the field strength under a current value. The conclusion was that tegafur magnetic thermosensitive liposomes with comparatively small particle size, superparamagnetism and comparatively strong magnetism were prepared successfully.
Databáze: OpenAIRE
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