Role of Bioactivation Reactions in Chemically Induced Nephrotoxicity

Autor:	Lawrence H. Lash
Rok vydání:	2022
Předmět:	chemistry.chemical_classification Kidney urogenital system Chemistry Pharmacology Nephrotoxicity Chemically Induced Toxicity chemistry.chemical_compound Enzyme medicine.anatomical_structure medicine Xenobiotic human activities Drug toxicity
Zdroj:	Pharmaceutical Sciences Encyclopedia
DOI:	10.1002/9781119851042.ch22
Popis:	Kidneys express a diverse array of enzymes that can catalyze the bioactivation of many drugs and xenobiotics. The kidneys are particularly susceptible to chemically induced toxicity because of their basic physiology and biochemistry. The article discusses the role of bioactive reactions in chemically induced nephrotoxicity. Keywords: nephrotoxicity; xenobiotics; kidney; bioactive reactions; drug toxicity
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb33f019b959a041ff6e172e461c711 https://doi.org/10.1002/9781119851042.ch22 Zobrazit plný text záznamu