Autor: |
Greta Barbieri, Luna Gargani, Vittoria Lepri, Stefano Spinelli, Chiara Romei, Annalisa De Liperi, Davide Chimera, Francesco Pistelli, Laura Carrozzi, Francesco Corradi, Lorenzo Ghiadoni, Joanne Spataro, Margherita Malacarne, Elisabetta Addante, Sabrina Agostini o Degl'Innocenti, Paolo De Carlo, Alessio Gregori, Sara Manieri, Chiara Deri, Sara Perelli, Arianna Sabattini, Simonetta Salemi, Federica Volpi, Leonardo Colligiani, Salvatore Claudio Fanni, Laura Tavanti, Roberta Pancani, Massimiliano Desideri, Nicoletta Carpenè, Luciano Gabbrielli, Alessandro Celi, Antonio Fideli, Chiara Cappiello, Claudia Meschi, Luca Visconti, Giovanna Manfredini, Ferruccio Aquilini |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
European journal of internal medicine. |
ISSN: |
1879-0828 |
Popis: |
During COVID-19 pandemic, lung ultrasound (LUS) proved to be of great value in the diagnosis and monitoring of patients with pneumonia. However, limited data exist regarding its use to assess aeration changes during follow-up (FU). Our study aims to prospectively evaluate 232 subjects who underwent a 3-month-FU program after hospitalization for COVID-19 at the University Hospital of Pisa. The goals were to assess the usefulness of standardized LUS compared with the gold standard chest computed tomography (CT) to evaluate aeration changes and to verify LUS and CT agreement at FU. Patients underwent in the same day a standardized 16-areas LUS and high-resolution chest CT reported by expert radiologists, assigning interpretative codes. Based on observations distribution, LUS score cut-offs of 3 and 7 were selected, corresponding to the 50th and 75th percentile, respectively. Patients with LUS scores above both these thresholds were older and with longer hospital stay. Patients with a LUS score ≥3 had more comorbidities. LUS and chest CT showed a high agreement in identifying residual pathological findings, using both cut-off scores of 3 (OR 14,7; CL 3,6-64,5, Sensitivity 91%, Specificity 49%) and 7 (OR 5,8; CL 2,3-14,3, Sensitivity 65%, Specificity 79%). Our data suggest that LUS is very sensitive in identifying pathological findings at FU after a hospitalization for COVID-19 pneumonia, compared to CT. Given its low cost and safety, LUS could replace CT in selected cases, such as in contexts with limited resources or it could be used as a gate-keeper examination before more advanced techniques. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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