Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats
| Autor: | Ping Cheng, Jian-min Si, Dong-fei Wang, Liangjing Wang, Fang-shi Zhu |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Gastritis
Atrophic Somatostatin-Secreting Cells medicine.medical_specialty Pathology Atrophic gastritis Cell Count Gastroenterology Rats Sprague-Dawley chemistry.chemical_compound Parietal Cells Gastric Internal medicine medicine Chief cell Gastric mucosa Animals Gastrin-Secreting Cells Pharmacology (medical) Enterochromaffin-like cell Parietal cell Inflammation Chief Cells Gastric Chemistry General Medicine medicine.disease Rats stomatognathic diseases Foveolar cell medicine.anatomical_structure Monomer Complementary and alternative medicine Gastric Mucosa Medicine public health Chronic Disease Aluminum Silicates Powders |
| Zdroj: | Chinese Journal of Integrative Medicine. 14:111-116 |
| ISSN: | 1993-0402 1672-0415 |
| DOI: | 10.1007/s11655-007-9003-5 |
| Popis: | To study the regulative action of mica monomer powder preparation on the chief and parietal cells as well as G and D cells in the gastric mucosa of the experimental atrophic gastritis (CAG) rats.Intervention therapy was given to the experimental CAG rats at three different doses of mica monomer powder preparation to evaluate the changes of chief and parietal cells as well as G and D cells in the gastric mucosa and the histopathological changes of gastric mucosa.Mica monomer powder preparation at three different doses could increase the amount of chief and parietal cells as well as G and D cells in gastric mucosa of the experimental CAG rats and alleviate and control the inflammation of gastric mucosa and the atrophy of gastric mucosa glands. Especially, better effects were shown in the mid and high dose groups.Mica has the pharmacological action of protecting the gastric mucosa, enhancing blood flow of the gastric mucosa, and consequently improving the inflammatory responses of the gastric mucosa. One of the mechanisms is associated with promoting the secretion of gastric acid and gastric pepsin and regulating the neuroendocrine mechanism including gut hormone secretion (gastrin and somatostatin) by increasing the number of chief and parietal cells as well as G and D cells. |
| Databáze: | OpenAIRE |
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