Urticarial erythema associated with IgA myeloma
| Autor: | Daizo Ueda, Satoshi Dekio, Eishin Morita, Yan Zhang, Hiroaki Matsuo |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Pathology medicine.medical_specialty Erythema Bone Marrow Cells Dermatology Immunofluorescence Lesion Diagnosis Differential immune system diseases Medicine Humans Multiple myeloma Aged integumentary system medicine.diagnostic_test business.industry General Medicine medicine.disease IgA myeloma Blood Cell Count Immunoglobulin A Bone marrow examination Serum protein electrophoresis medicine.symptom business Multiple Myeloma Infiltration (medical) Blood Chemical Analysis |
| Zdroj: | The Journal of dermatology. 31(8) |
| ISSN: | 0385-2407 |
| Popis: | We report a case of atypical urticaria associated with IgA multiple myeloma. A 79-year-old man presented with a two-month history of wheal-like erythema, which lasted approximately one week without any response to anti-histamines. Histological examination of a lesion revealed leukocytoclasia as well as perivascular leukocytic infiltration, being consistent with urticarial erythema. Laboratory investigation showed markedly elevated serum IgA concentration and M-protein in serum protein electrophoresis. A bone marrow examination led to a diagnosis of myeloma. An immunofluorescence study failed to detect any IgA deposit in the lesion. However, the wheal-like eruptions disappeared when the IgA myeloma was treated and reappeared when it relapsed. We conclude that this long lasting urticaria was the cutaneous manifestation of IgA myeloma. |
| Databáze: | OpenAIRE |
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