Quantitative ultrasound assessment of the influence of roughness and healing time on osseointegration phenomena
| Autor: | Benoit Lecuelle, S. Le Cann, Romain Vayron, H. Albini Lomami, Y. Hériveaux, Guillaume Haiat, C.H. Flouzat Lachaniette, Manon Fraulob |
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| Přispěvatelé: | Laboratoire Modélisation et Simulation Multi-Echelle (MSME), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Université Gustave Eiffel, Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201 (LAMIH), Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France), École nationale vétérinaire d'Alfort (ENVA), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Haiat, Guillaume, Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), École nationale vétérinaire - Alfort (ENVA) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
[SPI] Engineering Sciences [physics] Science 0206 medical engineering Healing time 02 engineering and technology Surface finish [SPI.MECA] Engineering Sciences [physics]/Mechanics [physics.med-ph] Bone tissue Osseointegration Article 03 medical and health sciences [SPI]Engineering Sciences [physics] 0302 clinical medicine Animal model Surface roughness medicine Animals Wound Healing Multidisciplinary 030206 dentistry Acoustics Prostheses and Implants [SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph] 020601 biomedical engineering Mechanical engineering Quantitative ultrasound medicine.anatomical_structure Preclinical research Time and Motion Studies Medicine Ultrasonic sensor Rabbits Biomedical engineering |
| Zdroj: | Scientific Reports Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1-12. ⟨10.1038/s41598-020-78806-0⟩ Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020) Scientific Reports, 2020, 10 (1), pp.1-12. ⟨10.1038/s41598-020-78806-0⟩ |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-78806-0⟩ |
| Popis: | The evolution of bone tissue quantity and quality in contact with the surface of orthopedic and dental implants is a strong determinant of the surgical outcome but remains difficult to be assessed quantitatively. The aim of this study was to investigate the performance of a quantitative ultrasound (QUS) method to measure bone-implant interface (BII) properties. A dedicated animal model considering coin-shaped titanium implants with two levels of surface roughness (smooth, Sa = 0.49 µm and rough, Sa = 3.5 µm) allowed to work with a reproducible geometry and a planar interface. The implants were inserted in rabbit femurs and tibiae for 7 or 13 weeks. The ultrasonic response of the BII was measured ex vivo, leading to the determination of the 2-D spatial variations of bone in contact with the implant surface. Histological analysis was carried out to determine the bone-implant contact (BIC) ratio. The amplitude of the echo was significantly higher after 7 weeks of healing time compared to 13 weeks, for both smooth (p p |
| Databáze: | OpenAIRE |
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