A case of erosive polyarthropathy from Medieval northern Italy (12th-13th centuries)
| Autor: | Marta Licata, Chiara Tesi, Valentina Giuffra, Monica Motto, Omar Larentis, Gino Fornaciari |
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| Rok vydání: | 2018 |
| Předmět: |
Male
History Archeology Adult male Radiographic imaging Middle ages Pathology and Forensic Medicine Arthritis Rheumatoid Rheumatoid Rheumatoid-like arthritis Osteoarthritis Medicine Humans Northern Italy 0601 history and archaeology Carpal Bones Skeleton Aged 060101 anthropology 060102 archaeology Erosive polyarthropathy Remission phase History Medieval Italy Middle Aged Radiography Tarsal Bones business.industry Arthritis Small sample 06 humanities and the arts Anatomy Northern italy Tarsal Bone Polyarthropathies Differential diagnosis Interphalangeal Joint business Medieval |
| Zdroj: | International journal of paleopathology. 25 |
| ISSN: | 1879-9825 |
| Popis: | Objective To evaluate and differentially diagnose erosive skeletal lesions located on multiple joints of an individual archaeologically recovered in 2017. Materials Skeletal remains of a well-preserved skeleton dating to the 12th–13th centuries from the medieval church of San Biagio in Cittiglio (Varese, northern Italy). Methods Macroscopic and radiographic imaging. Results Erosive marginal symmetrical lesions are present on the metatarsophalangeal, metacarpophalangeal and interphalangeal joints of an adult male, aged 55–75 years. Osteolytic changes, in the form of pocket erosions, surface resorptions and pseudocyst formations, are also macroscopically observed on some carpal and tarsal bones and on several large peripheral joints. Conclusions A careful differential diagnosis of the lesions and their macroscopic and radiological appearance is suggestive of a case of rheumatoid arthritis-like polyarthropathy. Significance This case contributes to the debate regarding the antiquity of erosive polyarthropathies, providing additional evidence for the existence of these diseases in the Old World prior to the European discovery of the Americas. Limitations Small sample size limits discussion of the scope of the disease in antiquity. Suggestions for further research This case highlights the need for further macroscopic, radiographic, and biomolecular studies of pre-modern European skeletal samples to investigate the hypothesized pre-existence of these pathological conditions in Europe prior to 1492. |
| Databáze: | OpenAIRE |
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