Hepatitis C virus infection in patients with chronic liver diseases
| Autor: | Norihisa Nishimura, Hiroyuki Tsujii, M. Kyo, Jyunichi Yamao, Akira Takaya, Hiroshige Nakano, Hiroshi Fukui, Noboru Tsukamoto, Tadasu Tsujii, Masahide Yoshikawa |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty Cirrhosis Hepatitis C virus Enzyme-Linked Immunosorbent Assay Chronic liver disease medicine.disease_cause Gastroenterology Seroepidemiologic Studies Internal medicine medicine Humans Hepatitis Antibodies Aged biology business.industry Liver Diseases virus diseases Hepatitis C Hepatitis B Hepatology Middle Aged medicine.disease digestive system diseases Hepatocellular carcinoma Chronic Disease biology.protein Female Antibody business |
| Zdroj: | Gastroenterologia Japonica. 26 |
| ISSN: | 0435-1339 |
| Popis: | Antibodies against hepatitis C (HCV) in 512 patients were measured by an enzyme immunoassay (Ortho-HCV ELISA). The frequency of anti-HCV was 80%, 86%, 85% in nonB (NB) chronic hepatitis (CH), cirrhosis (LC), hepatocellular carcinoma (HCC), respectively; 70%, 90% in alcoholic (AL) LC, HCC; 15%, 33%, 58% in hepatitis B (HB) CH, LC, HCC, respectively. Anti-HCV positive cirrhotics had a shorter survival time and earlier development of HCC than anti-HCV negative cirrhotics. The findings suggest that HCV is a major cause of NB chronic liver diseases and may play a pathogenetic role in AL and HB liver diseases. |
| Databáze: | OpenAIRE |
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