Elimination of Taenia solium transmission to pigs in a field trial of the TSOL18 vaccine in Cameroon

Autor:	Stanny Geerts, Marshall W. Lightowlers, Craig T. Kyngdon, Emmanuel Assana, Redgi De Deken, Garry A. Anderson, Charles G. Gauci, André Pagnah Zoli, Pierre Dorny
Rok vydání:	2010
Předmět:	Veterinary medicine Swine Neurocysticercosis 0302 clinical medicine Taenia solium Taeniasis Hosts Cameroon Anthelmintics Swine Diseases Vaccines 0303 health sciences Vaccination Helminthic diseases 3. Good health Animal diseases medicine.drug_formulation_ingredient Infectious Diseases Vaccines Subunit Pigs Rapid Communication Oxfendazole 030231 tropical medicine Immunization Secondary Biology Quillaja Saponins 03 medical and health sciences Adjuvants Immunologic Control parasitic diseases medicine Animals Helminths Field trial Africa Central Field trials ComputingMethodologies_COMPUTERGRAPHICS 030304 developmental biology Cestodes Vaccine trial TSOL18 Saponins medicine.disease Virology Parasitology Antigens Helminth Oxfendazol Benzimidazoles
Zdroj:	International Journal for Parasitology
ISSN:	0020-7519
DOI:	10.1016/j.ijpara.2010.01.006
Popis:	Graphical abstract A pilot field trial of the TSOL18 vaccine was undertaken in Cameroon. Two hundred and forty, 2–3 month-old piglets were distributed to 114 individual households in pairs. Vaccinated animals received three immunisations with 200 μg TSOL18 plus 5 mg Quil A and 30 mg/kg oxfendazole at the time of the second immunisation. Necropsies were undertaken when the pigs were approximately 12 months of age. Viable Taenia solium cysticerci were identified in 20 control pigs (prevalence 19.6%); no cysticerci were found in any of the vaccinated animals (P
Databáze:	OpenAIRE
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