Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients’
| Autor: | Samarjit Dey, Karim Hmr, P. Bhattacharyya, Borthakur Mp, Md. Yunus, Angkita Barman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pediatrics Clinical Biochemistry lcsh:Medicine 03 medical and health sciences 0302 clinical medicine Intensive care Internal medicine Severity of illness medicine Illness severity Hypocalcaemia 030212 general & internal medicine calcium APACHE II critical illnesses business.industry lcsh:R General Medicine Anaesthesia Section medicine.disease critical care Health evaluation Relative risk SOFA score business critical care outcome 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 11, Iss 3, Pp UC01-UC03 (2017) |
| Popis: | Introduction: Hypocalcaemia is very much prevalent in critically ill patients yet very less is known about its association with severity of illness. Acute Physiology and Chronic Health Evaluation (APACHE) and Sequential Organ Failure Assessment (SOFA) are two commonly used and validated scoring tool used to assess the severity of illness in critically ill patients. Aim: To analyze the relation of on admission hypocalcaemia with severity of illness as measured by APACHE-II and SOFA scores. Materials and Methods: After institute approval, 111 patients admitted during May to June 2016 were evaluated. Age, sex, on admission, ionized calcium (iCa0) levels, first day APACHEII and SOFA scores were collected. Data were then divided in different classes based on iCa0 levels (i.e., normocalcaemic, mild, moderate and severe hypocalcaemic), APACHE-II and SOFA scores and their relationship was assessed using INSTAT software (GraphPad Software, Inc, La Zolla, CA, USA) with appropriate statistical tests. Results: Seventy eight (70.27%) patients were having hypocalcaemia on admission ( 20 were significantly lower than patients with APACHE-II < 9 (0.88±0.26 versus 1.09±0.24, p 9 were not significantly lower than patients with SOFA < 4 (0.99±0.41 versus 1.04±0.23, p > 0.05). The relative risk of on admission hypocalcaemia across increasing illness severity was also not statistically significant. Both relative risk of mortality and length of ICU stay were higher in on admission moderate hypocalcaemic patients as compared to normocalcaemic but the difference was not statistically significant. Conclusion: On admission, hypocalcaemia has inconsistent correlation with increasing illness severity in adult intensive care patients. iCa0 of 0.81–0.90 mmol/L appears to have maximum deleterious effect with regard to mortality and length of ICU stay. |
| Databáze: | OpenAIRE |
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