Understanding the implications of SARS-CoV-2 re-infections on immune response milieu, laboratory tests and control measures against COVID-19
| Autor: | Amos Dangana, Idris Nasir Abdullahi, Justin Onyebuchi Nwofe, Charles Egede Ugwu, Ovye Engom Godiya Alaba, Yakubu Kokori Enevene Ibrahim, Maijidda Saidu Aminu, Nkechi Blessing Ugboaja, Silifat Oyewusi, Dorcas Aliyu, Peter Elisha Ghamba, Olawale Sunday Animasaun, Folake Olubunmi Ajayi, Hadiza Yahaya, Solomon Oloche Onoja, Samuel Ayobami Fasogbon, Sharafudeen Dahiru Abubakar, Chikodi Modesta Umeozuru, Abdulmumuni Samuel Aliyu, Halima Ali Shuwa, Wudi Natasha Tanko, Anthony Uchenna Emeribe, Pius Omoruyi Omosigho, Jelili Olaide Mustapha, Mala Alhaji Baba Mallam, Odunayo O.R. Ajagbe |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Protective immunity Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses Infection control Review Article 03 medical and health sciences 0302 clinical medicine Immune system Pandemic Medicine Diagnostic laboratory lcsh:Social sciences (General) skin and connective tissue diseases lcsh:Science (General) SARS-CoV-2 re-infection Multidisciplinary business.industry Immune evasion fungi Outbreak virus diseases COVID-19 body regions Diagnostic challenges 030104 developmental biology Immunology lcsh:H1-99 business 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Heliyon, Vol 7, Iss 1, Pp e05951-(2021) Heliyon |
| ISSN: | 2405-8440 |
| Popis: | Several months after the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), cases of re-infection after recovery were reported. The extent and duration of protective immunity after SARS-CoV-2 infection is not fully understood. As such, the possibility of re-infection with SARS-CoV-2. Furthermore, cases of re-infection were mainly due to different variants or mutant SARS-CoV-2. Following the fast and pandemic-scale spread of COVID-19, mutations in SARS-CoV-2 have raised new diagnostic challenges which include the redesign of the oligonucleotide sequences used in RT-PCR assays to avoid potential primer–sample mismatches, and decrease sensitivities. Since the initial wave of the pandemic, some regions had experienced fresh outbreaks, predisposing people to be susceptible to SARS-CoV-2 re-infection. Hence, this article sought to offer detailed biology of SARS-CoV-2 re-infections and their implications on immune response milieu, diagnostic laboratory tests and control measures against COVID-19. SARS-CoV-2 re-infection, Diagnostic challenges, Immune evasion, Infection control, COVID-19. |
| Databáze: | OpenAIRE |
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