Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan
| Autor: | Yeh Sheng Chien, Tzou Yien Lin, Yhu Chering Huang, Min Shi Lee, Ying Hsiang Wang, Kuo Chien Tsao, Shu Ting Luo |
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| Rok vydání: | 2018 |
| Předmět: |
Disease
Genome Viral Global Health Genome DNA sequencing Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Hepatolenticular Degeneration Enterovirus Infections Medicine Humans Phylogeny Retrospective Studies Genetics Enterovirus D Human lcsh:R5-920 Molecular epidemiology business.industry Strain (biology) Outbreak General Medicine Sequence Analysis DNA medicine.disease Wilson's disease 030220 oncology & carcinogenesis Child Preschool 030211 gastroenterology & hepatology Female lcsh:Medicine (General) business Enterovirus D68 |
| Zdroj: | Journal of the Formosan Medical Association, Vol 118, Iss 2, Pp 641-646 (2019) |
| ISSN: | 0929-6646 |
| Popis: | North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained from the public domain, it was classified as genome type 1-B; it is phylogenetically related to the predominant EV-D68 viruses that circulated in 2009 in Vietnam. It is necessary to strengthen EV-D68 detection globally, including in children with acute liver failure. Moreover, harmonization of genomic analysis of EV-D68 is desirable to understand global evolution of EV-D68. Keywords: Enterovirus D68, Genome study, Molecular epidemiology, Next-generation sequencing |
| Databáze: | OpenAIRE |
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