Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
| Autor: | Matthew Butawan, Rodney L. Benjamin, Richard J. Bloomer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Methylsulfonylmethane medicine.medical_specialty Dose Dietary supplement Anti-Inflammatory Agents Biological Availability lcsh:TX341-641 Review Pharmacology Antioxidants dimethyl sulfone 03 medical and health sciences chemistry.chemical_compound Risk Factors Neoplasms Hypersensitivity Medicine Animals Humans Dimethyl Sulfoxide MSM Sulfones Intensive care medicine Inflammation Nutrition and Dietetics Dose-Response Relationship Drug business.industry Arthritis Outcome measures Myalgia Clinical trial Antioxidant capacity Disease Models Animal Oxidative Stress 030104 developmental biology Cartilage chemistry Time course Dietary Supplements joint pain inflammation methylsulfonylmethane business lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Nutrients Nutrients, 9(3):290 Nutrients, Vol 9, Iss 3, p 290 (2017) |
| ISSN: | 2072-6643 |
| Popis: | Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety of purposes, including its most common use as an anti-inflammatory agent. It has been well-investigated in animal models, as well as in human clinical trials and experiments. A variety of health-specific outcome measures are improved with MSM supplementation, including inflammation, joint/muscle pain, oxidative stress, and antioxidant capacity. Initial evidence is available regarding the dose of MSM needed to provide benefit, although additional work is underway to determine the precise dose and time course of treatment needed to provide optimal benefits. As a Generally Recognized As Safe (GRAS) approved substance, MSM is well-tolerated by most individuals at dosages of up to four grams daily, with few known and mild side effects. This review provides an overview of MSM, with details regarding its common uses and applications as a dietary supplement, as well as its safety for consumption. |
| Databáze: | OpenAIRE |
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