Transcriptional Regulation of Adrenocortical Steroidogenic Gene Expression

Autor:	Eric B. Dammer, Marion B. Sewer, Srinath Jagarlapudi
Rok vydání:	2007
Předmět:	Steroidogenic factor 1 Transcription Genetic Adrenal cortex Gene Expression Regulation Developmental DNA Peptide hormone Biology Angiotensin II medicine.anatomical_structure Adrenocorticotropic Hormone Cytochrome P-450 Enzyme System Gene Expression Regulation Biochemistry Gene expression Adrenal Cortex Transcriptional regulation medicine Animals Humans Steroids Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics Signal Transduction Hormone Steroid Hydroxylases
Zdroj:	Drug Metabolism Reviews. 39:371-388
ISSN:	1097-9883 0360-2532
DOI:	10.1080/03602530701498828
Popis:	By serving as ligands for nuclear and plasma membrane receptors, steroid hormones are key regulators of a diverse array of physiological processes. These hormones are synthesized from cholesterol in tissues such as the adrenal cortex, ovaries, testes, and placenta. Because steroid hormones control the expression of numerous genes, steroidogenic cells utilize multiple mechanisms that ensure tight control of the synthesis of these molecules. This review will give an overview of the molecular mechanisms by which the expression of steroidogenic genes is regulated in the human adrenal cortex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7872401b1337a5f072710dcfe65e4d https://doi.org/10.1080/03602530701498828 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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